Research interests and approaches: Most of my research has focused on circadian rhythms, largely utilizing in vitro electrophysiological recordings and protein assays of the mammalian suprachiasmatic nucleus (SCN) circadian clock. These projects investigated cellular mechanisms through which mammalian circadian clock phase can be modulated, including intracellular signal transduction processes, receptor pharmacology, and extracellular signaling molecules. Current projects focus on excitotoxicity across different brain regions in response to over-stimulation or neurodegenerative diseases. These collaborative endeavors involve a broad mix of techniques, including microscopy, microfluidics, calcium imaging, and analyzing changes in the expression of cytokines, proteins, lipids, and RNAs.